Deep learning-assisted tumor radiomic dynamics on MRI predict pathological complete response in HCC undergoing immune-based therapy followed by hepatectomy

Dynamic radiomic changes effectively predict pCR in uHCC after conversion therapy. Combining delta radiomics with AFP response significantly improves predictive performance, offering a non-invasive method for assessing pCR and potentially guiding personalized treatment decisions.

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Publication Details

Journal
Hepatology
Published
2026-02-26
DOI
https://doi.org/10.1097/hep.0000000000001724
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
0.00
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article

Deep learning-assisted tumor radiomic dynamics on MRI predict pathological complete response in HCC undergoing immune-based therapy followed by hepatectomy

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Hepatology
Radiomics and Machine Learning in Medical Imaging
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Deep learning-assisted tumor radiomic dynamics on MRI predict pathological complete response in HCC undergoing immune-based therapy followed by hepatectomy

Qi Gao, He Tian, Lu-Na Wang, Liyu Sun, Wu Lw, Fei Li, Shiqi Zhou, HUI-CHUAN SUN, Yuehua Chen, Ying-Hao Shen, C. Huang, B. Xu, Zi-Yue Yang, Fan Jia, Xiao-Dong Zhu, Jian Zhou, Tian-Qiang Song, Zi-Yi Wang, Hui Li, Ling-Li Chen, Yuan Ji
article en

Abstract

Dynamic radiomic changes effectively predict pCR in uHCC after conversion therapy. Combining delta radiomics with AFP response significantly improves predictive performance, offering a non-invasive method for assessing pCR and potentially guiding personalized treatment decisions.

Hepatology
Shanghai Medical College of Fudan University (CN), Sun Yat-sen University (CN), Fudan University (CN), Ruijin Hospital (CN), Tianjin Medical University Cancer Institute and Hospital (CN), Zhongshan Hospital (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), United Imaging Healthcare (China) (CN)
Good health and well-being
Openalex Percentile: Top 43%
Radiomics and Machine Learning in Medical Imaging
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