Calcitonin Gene-Related Peptide (CGRP) Expression in Somatotroph Adenomas: Implications for Clinical Course and Treatment Outcomes

CGRP was found to be notably present in somatotropin-producing adenoma tissues, yet it was entirely absent from non-functioning adenoma tissues. The detection of CGRP within adenoma tissue could correlate with an increased incidence of persistent headaches and diminished postoperative remission probabilities in acromegaly.

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Publication Details

Journal
Neuroendocrinology
Published
2026-02-26
DOI
https://doi.org/10.1159/000551012
Primary Topic
Neuropeptides and Animal Physiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Calcitonin Gene-Related Peptide (CGRP) Expression in Somatotroph Adenomas: Implications for Clinical Course and Treatment Outcomes

Fatih Mert Doğukan, Hüseyin Karatay, Mehmet Said Cil, Sanem Cil et al.
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Neuropeptides and Animal Physiology
article

Calcitonin Gene-Related Peptide (CGRP) Expression in Somatotroph Adenomas: Implications for Clinical Course and Treatment Outcomes

Fatih Mert Doğukan, Hüseyin Karatay, Mehmet Said Cil, Sanem Cil, Buruc Erkan, Aslihan Pekmezci, Ebubekir Akpinar, Sebnem Burhan, Esra Hatipoglu, Mutlu Niyazoglu
article en

Abstract

CGRP was found to be notably present in somatotropin-producing adenoma tissues, yet it was entirely absent from non-functioning adenoma tissues. The detection of CGRP within adenoma tissue could correlate with an increased incidence of persistent headaches and diminished postoperative remission probabilities in acromegaly.

Neuroendocrinology
Good health and well-being
Openalex Percentile: Top 43%
Neuropeptides and Animal Physiology
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