Successful Management of <i>Candida auris</i> Bloodstream Infection in an Elderly Patient: A Case Report

<i>Candida auris</i> is an emerging multidrug-resistant pathogen frequently misidentified by conventional methods, posing diagnostic and infection-control challenges, particularly in low- and middle-income countries. We report a 74-year-old male in Dhaka, Bangladesh, with multiple comorbidities who developed Candidemia. Blood culture yielded Gram-positive budding yeast with inconclusive conventional carbohydrate tests. The isolate was identified as <i>C. auris</i> using Vitek 2 (software v8.01) and confirmed by ITS sequencing (GenBank accession MZ323988). Phylogenetic analysis showed clustering with global strains. Antifungal susceptibility testing indicated resistance to fluconazole and amphotericin B, with susceptibility to echinocandins. Intravenous micafungin was started based on susceptibility results and guideline recommendations. The patient responded gradually to the treatment, recovered fully, and was discharged after 21 days of admission. This case highlights the importance of rapid species-level identification and access to confirmatory molecular testing to guide effective treatment and infection prevention in resource-limited settings.

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Publication Details

Journal
Clinical Case Reports
Published
2026-02-23
DOI
https://doi.org/10.1002/ccr3.72048
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

Successful Management of Candida auris Bloodstream Infection in an Elderly Patient: A Case Report

Tuhin Sadique, Ahmed Abdullah, Md Nazrul Islam, Asif Khan et al.
Clinical Case Reports
Antifungal resistance and susceptibility
article

Successful Management of Candida auris Bloodstream Infection in an Elderly Patient: A Case Report

Tuhin Sadique, Ahmed Abdullah, Md Nazrul Islam, Asif Khan, Dilruba Ahmed, Debashis Sen, Arif Hasan Chowdhury, Dinesh Mondal, Tania Rahman
article en

Abstract

<i>Candida auris</i> is an emerging multidrug-resistant pathogen frequently misidentified by conventional methods, posing diagnostic and infection-control challenges, particularly in low- and middle-income countries. We report a 74-year-old male in Dhaka, Bangladesh, with multiple comorbidities who developed Candidemia. Blood culture yielded Gram-positive budding yeast with inconclusive conventional carbohydrate tests. The isolate was identified as <i>C. auris</i> using Vitek 2 (software v8.01) and confirmed by ITS sequencing (GenBank accession MZ323988). Phylogenetic analysis showed clustering with global strains. Antifungal susceptibility testing indicated resistance to fluconazole and amphotericin B, with susceptibility to echinocandins. Intravenous micafungin was started based on susceptibility results and guideline recommendations. The patient responded gradually to the treatment, recovered fully, and was discharged after 21 days of admission. This case highlights the importance of rapid species-level identification and access to confirmatory molecular testing to guide effective treatment and infection prevention in resource-limited settings.

Clinical Case ReportsVol. 14(3)
International Centre for Diarrhoeal Disease Research (BD), University of Virginia (US)
No poverty
Openalex Percentile: Top 42%
Antifungal resistance and susceptibility
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