Protocol for a multicentre target trial emulation comparing ketamine and propofol in critically ill adults undergoing emergency intubation
This target trial emulation will provide real-world causal evidence comparing ketamine versus propofol induction for high-risk emergency intubation, with the potential to inform practice, protocols, and future randomised trials.
Authors
- Tapan Parikh aka Parmar
- Rafael von Hellmann (ORCID: https://orcid.org/0000-0001-6098-7052)
- Michael Toolis (ORCID: https://orcid.org/0009-0000-6285-5440)
- Ryan Ruiyang Ling (ORCID: https://orcid.org/0000-0002-8335-7640)
- Ashwin Subramaniam
Institutions
- National University of Singapore (SG)
- Peninsula Health (AU)
- Dandenong Hospital (AU)
- National University Health System (SG)
- Monash University (AU)
Publication Details
- Journal
- Critical Care and Resuscitation
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1016/j.ccrj.2026.100171
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00