Trametinib and Fimepinostat Induce Malignant Peripheral Nerve Sheath Tumor Cell Death In Vitro

These studies demonstrate <i>in vitro</i> efficacy for two candidate MPNST therapeutics which could reduce tumor burden and metastasis in NF1 patients.

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Publication Details

Journal
Cancers
Published
2026-02-26
DOI
https://doi.org/10.3390/cancers18050746
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
0.00
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article

Trametinib and Fimepinostat Induce Malignant Peripheral Nerve Sheath Tumor Cell Death In Vitro

Sofia Ares Oliveira, Cristina Fernandez-Valle, Ethan W. Hass
Cancers
Neurofibromatosis and Schwannoma Cases
article

Trametinib and Fimepinostat Induce Malignant Peripheral Nerve Sheath Tumor Cell Death In Vitro

Sofia Ares Oliveira, Cristina Fernandez-Valle, Ethan W. Hass
article en

Abstract

These studies demonstrate <i>in vitro</i> efficacy for two candidate MPNST therapeutics which could reduce tumor burden and metastasis in NF1 patients.

CancersVol. 18(5)
University of Central Florida (US)
Good health and well-being
Openalex Percentile: Top 47%
Neurofibromatosis and Schwannoma Cases
DOIOpen Access PDFOpenAlex
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