Vaginal Ulcers Secondary to Stage Iv Uterine Prolapse Treated With L‐PRF

Pelvic organs prolapse (POP) is usually used to describe the pelvic organs' descent into or through the vagina. The related common complications are bleeding, extrusion, vaginal discharge, pain, and constipation; only older women and those with comorbidities seem to be most prone to persist with their use. Surgery is preferred, instead, by younger active women with advanced prolapse symptoms. The uterus lowers and slides into the vagina. Treatment varies by stage and severity. The purpose of this article was to evaluate the efficacy of LPRP in the treatment ofuterine ulcers in an old 93 years' obese patient with UP stage IV non-surgically treatable. Obese 93-year-old woman with medical history of left hip replacement, bilateral knee replacement COPD with chronic pulmonary heart disease, renal failure, chronic heart failure, one hospitalization for acute heart failure, suffering from umbilical hernia, hypertension, hyperuricemia, polyhydric arthrosis, has had a complete uterine prolapse (grade IV) for 5 years. The patient has multiple vaginal ulcers as a consequence of urinary and fecal incontinence fluid in continuous contact with the occasionally inflamed everted vaginal mucosa. The ulcer area was infiltrated with L-PRF membranes and covered with PRF, which were sutured and protected with an inverted glove. The results of the present case report show the positive effect of L-PRF on the uterine ulcers that is a promising treatment for vaginal ulcers in case of prolapse. In conclusion, L-PRF has shown significant potential as an effective treatment for chronic non-healing uterine ulcers, offering advantages over conventional dressings in terms of efficacy, safety, and cost-effectiveness.

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Publication Details

Journal
Clinical Case Reports
Published
2026-02-24
DOI
https://doi.org/10.1002/ccr3.72098
Primary Topic
Pelvic floor disorders treatments
Type
article
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article

Vaginal Ulcers Secondary to Stage Iv Uterine Prolapse Treated With L‐PRF

A Greco Lucchina, Enrico Rescigno, Canata Alessandra, Gianluca Nicolai
Clinical Case Reports
Pelvic floor disorders treatments
article

Vaginal Ulcers Secondary to Stage Iv Uterine Prolapse Treated With L‐PRF

A Greco Lucchina, Enrico Rescigno, Canata Alessandra, Gianluca Nicolai
article en

Abstract

Pelvic organs prolapse (POP) is usually used to describe the pelvic organs' descent into or through the vagina. The related common complications are bleeding, extrusion, vaginal discharge, pain, and constipation; only older women and those with comorbidities seem to be most prone to persist with their use. Surgery is preferred, instead, by younger active women with advanced prolapse symptoms. The uterus lowers and slides into the vagina. Treatment varies by stage and severity. The purpose of this article was to evaluate the efficacy of LPRP in the treatment ofuterine ulcers in an old 93 years' obese patient with UP stage IV non-surgically treatable. Obese 93-year-old woman with medical history of left hip replacement, bilateral knee replacement COPD with chronic pulmonary heart disease, renal failure, chronic heart failure, one hospitalization for acute heart failure, suffering from umbilical hernia, hypertension, hyperuricemia, polyhydric arthrosis, has had a complete uterine prolapse (grade IV) for 5 years. The patient has multiple vaginal ulcers as a consequence of urinary and fecal incontinence fluid in continuous contact with the occasionally inflamed everted vaginal mucosa. The ulcer area was infiltrated with L-PRF membranes and covered with PRF, which were sutured and protected with an inverted glove. The results of the present case report show the positive effect of L-PRF on the uterine ulcers that is a promising treatment for vaginal ulcers in case of prolapse. In conclusion, L-PRF has shown significant potential as an effective treatment for chronic non-healing uterine ulcers, offering advantages over conventional dressings in terms of efficacy, safety, and cost-effectiveness.

Clinical Case ReportsVol. 14(3)
University of Rome Tor Vergata (IT), University of Chieti-Pescara (IT), Saint Camillus International University of Health and Medical Sciences (IT), Azienda Unità Sanitaria Locale Della Romagna (IT)
Zero hunger
Openalex Percentile: Top 45%
Pelvic floor disorders treatments
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