Network-targeted TMS modulates nicotine craving and default mode network connectivity in psychotic disorders

We identified a potential mechanism of nicotine use in psychosis and demonstrated that engaging this target reduces craving, suggesting a novel target for nicotine interventions in psychosis.

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Publication Details

Journal
Brain stimulation
Published
2026-02-26
DOI
https://doi.org/10.1016/j.brs.2026.103064
Primary Topic
Neurotransmitter Receptor Influence on Behavior
Type
article
Field-Weighted Citation Impact
0.00

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article

Network-targeted TMS modulates nicotine craving and default mode network connectivity in psychotic disorders

Sophia H. Blyth, Carol A. Tamminga, Jillian Connolly, Meda Shashwath et al.
Brain stimulation
Neurotransmitter Receptor Influence on Behavior
article

Network-targeted TMS modulates nicotine craving and default mode network connectivity in psychotic disorders

Sophia H. Blyth, Carol A. Tamminga, Jillian Connolly, Meda Shashwath, Heather Burrell Ward, Gulcan Yildiz, Mark A. Halko, Jennifer E. McDowell, Brett A. Clementz, V M SIMON, Baxter P. Rogers, Godfrey Pearlson, Elliot Gershon, Roscoe O. Brady
article en

Abstract

We identified a potential mechanism of nicotine use in psychosis and demonstrated that engaging this target reduces craving, suggesting a novel target for nicotine interventions in psychosis.

Brain stimulationVol. 19(2)
Beth Israel Deaconess Medical Center (US), Harvard University (US), University of Georgia (US), McLean Hospital (US), Yale University (US), University of Chicago (US), The University of Texas Southwestern Medical Center (US), Vanderbilt University Medical Center (US)
Vanderbilt University, National Institutes of Health, Vanderbilt Kennedy Center, Vanderbilt University Medical Center
Zero hunger
Openalex Percentile: Top 43%
Neurotransmitter Receptor Influence on Behavior
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