Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation

Overall, our study identified a novel cuproptosis-based predictive model, and we demonstrated that cuproptosis is a promising therapeutic method for THCA, which enhances our understanding of the cuproptosis-related genes and provides valuable insights into the clinical treatment and molecular mechanisms of THCA.

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Publication Details

Journal
Frontiers in Genetics
Published
2026-02-26
DOI
https://doi.org/10.3389/fgene.2026.1735093
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation

Shitong Su, Jiaqi Han, Kun Tian, Zijian Liu
Frontiers in Genetics
Ferroptosis and cancer prognosis
article

Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation

Shitong Su, Jiaqi Han, Kun Tian, Zijian Liu
article en

Abstract

Overall, our study identified a novel cuproptosis-based predictive model, and we demonstrated that cuproptosis is a promising therapeutic method for THCA, which enhances our understanding of the cuproptosis-related genes and provides valuable insights into the clinical treatment and molecular mechanisms of THCA.

Frontiers in GeneticsVol. 17
Sichuan University (CN), West China Second University Hospital of Sichuan University (CN), Sichuan Cancer Hospital (CN)
Good health and well-being
Openalex Percentile: Top 43%
Ferroptosis and cancer prognosis
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