Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation
Overall, our study identified a novel cuproptosis-based predictive model, and we demonstrated that cuproptosis is a promising therapeutic method for THCA, which enhances our understanding of the cuproptosis-related genes and provides valuable insights into the clinical treatment and molecular mechanisms of THCA.
Authors
- Shitong Su
- Jiaqi Han
- Kun Tian
- Zijian Liu
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- Sichuan Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3389/fgene.2026.1735093
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00