TLR7 Agonist Imiquimod Improves the Therapeutic Antitumor Effect of High–Dose–Rate Brachytherapy
The combination of IMQ with HDR brachytherapy induces a synergistic effect, improving the therapeutic antitumor effect of brachytherapy. Our data indicate that it is reasonable to use drugs that prevent changes in the TME in combination with radiotherapy.
Authors
- Ewelina Pilny (ORCID: https://orcid.org/0000-0003-1483-4543)
- Zbigniew Urbaś
- Alina Drzyzga (ORCID: https://orcid.org/0000-0001-5742-0821)
- Piotr Wojcieszek (ORCID: https://orcid.org/0000-0002-8347-4142)
- Ryszard Smolarczyk (ORCID: https://orcid.org/0000-0002-1131-289X)
- Justyna Czapla
- Joanna Ciepła
- M. Szlag
- Dorota Sprus-Lipka
- Magdalena Jarosz-Biej
- Tomasz Cichoń
- Karolina Sinek
Institutions
- National Institute of Oncology (HU)
- The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
Publication Details
- Journal
- Cancers
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3390/cancers18050745
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Narodowym Centrum Nauki
- National Institutes of Health