Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

Lower blood lactate is associated with increased risk for earlier death and greater weight loss in ALS, suggesting that lactate is a prognostic biomarker of nutritional status. ANN NEUROL 2026.

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Publication Details

Journal
Annals of Neurology
Published
2026-02-26
DOI
https://doi.org/10.1002/ana.78184
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

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Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

Shuhei Kobashi, Nobuhiro Ogawa, Ryutaro Nakamura, Shyuan Ngo, Isamu Yamakawa, Akihiro Kitamura, Makoto Urushitani, Robert D Henderson, Frederik J Steyn
article en

Abstract

Lower blood lactate is associated with increased risk for earlier death and greater weight loss in ALS, suggesting that lactate is a prognostic biomarker of nutritional status. ANN NEUROL 2026.

Annals of Neurology
Shiga University of Medical Science (JP), The University of Queensland (AU), Shiga University (JP), Royal Brisbane and Women's Hospital (AU)
Zero hunger
Openalex Percentile: Top 47%
Amyotrophic Lateral Sclerosis Research
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