Effects of tacrolimus treatment on the gut microbiota and metabolites in liver transplant recipients

Tacrolimus treatment is associated with distinct alterations in gut microbiota and metabolites among LT recipients. These findings provide a preliminary framework for future investigations aimed at optimizing immunosuppressive regimens, although their clinical translational potential requires validation in larger-scale, prospective cohort studies.

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Publication Details

Journal
PLoS ONE
Published
2026-02-26
DOI
https://doi.org/10.1371/journal.pone.0343817
Primary Topic
Gut microbiota and health
Type
article
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0.00
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article

Effects of tacrolimus treatment on the gut microbiota and metabolites in liver transplant recipients

Guohui Wang, Cangsang Song, Panpan Mao, Hanshu Zhang et al.
PLoS ONE
Gut microbiota and health
article

Effects of tacrolimus treatment on the gut microbiota and metabolites in liver transplant recipients

Guohui Wang, Cangsang Song, Panpan Mao, Hanshu Zhang, Xiaofang Zhang, Lu Liu, Xingde Li, Saijuan Lu
article en

Abstract

Tacrolimus treatment is associated with distinct alterations in gut microbiota and metabolites among LT recipients. These findings provide a preliminary framework for future investigations aimed at optimizing immunosuppressive regimens, although their clinical translational potential requires validation in larger-scale, prospective cohort studies.

PLoS ONEVol. 21(2)
Kunming Medical University (CN), The First Hospital of Kunming (CN), First Affiliated Hospital of Kunming Medical University (CN)
Good health and well-being
Openalex Percentile: Top 42%
Gut microbiota and health
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