A transparent AI assurance and benchmarking framework for EEG seizure detection on TUSZ seeded with a reproducible gradient-boosting ensemble

Reliable evaluation is essential for clinically usable automated electroencephalography (EEG) seizure detection. Although the TUH EEG Seizure Corpus (TUSZ) is the de facto benchmark, studies often use non-canonical splits, mix patients across partitions, or evaluate on seizure-only segments, making results hard to compare. We release an open-source, transparent benchmark for offline binary seizure detection on TUSZ v2.0.3 that strictly follows the official Train/Dev/Eval partition and evaluates in continuous EEG. Each 60-s window (15-s stride) is mapped to expert features and classified by three CatBoost ensembles: a within-window base model and two temporal-context models (full and high-sensitivity). We cast operating-point selection as an alarm-budget decision problem: on the Development set, we jointly choose the score threshold and event post-processing to maximize event sensitivity while enforcing specificity ≥ 0.93 and false alarms ≤ 0.69 per hour, then freeze this decision policy and apply it once to the held-out Eval set. On Eval, we obtain AUROC 0.92 and balanced accuracy 0.83 at the window level and event sensitivity 0.75 at 0.68 false alarms/hour (time-based positive predictive value [PPV] 0.57; recall 0.76). We provide the protocol and results as a reproducible baseline and clinically oriented benchmark for comparing past and future models.

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Publication Details

Journal
Scientific Reports
Published
2026-02-27
DOI
https://doi.org/10.1038/s41598-026-41358-w
Primary Topic
EEG and Brain-Computer Interfaces
Type
article
Field-Weighted Citation Impact
0.00

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article

A transparent AI assurance and benchmarking framework for EEG seizure detection on TUSZ seeded with a reproducible gradient-boosting ensemble

Morteza Zabihi, Kan Ding, Emily J. Gilmore, Eric S. Rosenthal
Scientific Reports
EEG and Brain-Computer Interfaces
article

A transparent AI assurance and benchmarking framework for EEG seizure detection on TUSZ seeded with a reproducible gradient-boosting ensemble

Morteza Zabihi, Kan Ding, Emily J. Gilmore, Eric S. Rosenthal
article en

Abstract

Reliable evaluation is essential for clinically usable automated electroencephalography (EEG) seizure detection. Although the TUH EEG Seizure Corpus (TUSZ) is the de facto benchmark, studies often use non-canonical splits, mix patients across partitions, or evaluate on seizure-only segments, making results hard to compare. We release an open-source, transparent benchmark for offline binary seizure detection on TUSZ v2.0.3 that strictly follows the official Train/Dev/Eval partition and evaluates in continuous EEG. Each 60-s window (15-s stride) is mapped to expert features and classified by three CatBoost ensembles: a within-window base model and two temporal-context models (full and high-sensitivity). We cast operating-point selection as an alarm-budget decision problem: on the Development set, we jointly choose the score threshold and event post-processing to maximize event sensitivity while enforcing specificity ≥ 0.93 and false alarms ≤ 0.69 per hour, then freeze this decision policy and apply it once to the held-out Eval set. On Eval, we obtain AUROC 0.92 and balanced accuracy 0.83 at the window level and event sensitivity 0.75 at 0.68 false alarms/hour (time-based positive predictive value [PPV] 0.57; recall 0.76). We provide the protocol and results as a reproducible baseline and clinically oriented benchmark for comparing past and future models.

Scientific Reports
Harvard University (US), Yale University (US), Massachusetts General Hospital (US), The University of Texas Southwestern Medical Center (US)
Massachusetts General Hospital, National Institutes of Health, National Institute of Neurological Disorders and Stroke
Gender equality
Openalex Percentile: Top 45%
EEG and Brain-Computer Interfaces
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