The predictive value of circulating inflammatory and immune biomarkers for stroke-associated pneumonia following endovascular therapy in patients with acute anterior circulation large vessel occlusion infarction: a prospective cohort study

In this exploratory study, our findings suggest that mHLA-DR expression levels may indicate some predictive value for SAP development after EVT in ACLVO patients, with the predictive performance appearing enhanced when combined with the A2DS2 score. Dysphagia and a large infarct volume emerged as potential risk factors for SAP. Conversely, within the context of our cohort, plasma levels of IL-6, CRP, and PCT did not demonstrate clear utility for the early prediction of SAP.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-02-26
DOI
https://doi.org/10.3389/fneur.2026.1764204
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00

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article

The predictive value of circulating inflammatory and immune biomarkers for stroke-associated pneumonia following endovascular therapy in patients with acute anterior circulation large vessel occlusion infarction: a prospective cohort study

Lin Tian, Zhuquan Hong, Z Zhu, Xiaorong Zhang et al.
Frontiers in Neurology
Neuroinflammation and Neurodegeneration Mechanisms
article

The predictive value of circulating inflammatory and immune biomarkers for stroke-associated pneumonia following endovascular therapy in patients with acute anterior circulation large vessel occlusion infarction: a prospective cohort study

Lin Tian, Zhuquan Hong, Z Zhu, Xiaorong Zhang, Pingzhen LIN, Quanlong Hong, Biyu Wu
article en

Abstract

In this exploratory study, our findings suggest that mHLA-DR expression levels may indicate some predictive value for SAP development after EVT in ACLVO patients, with the predictive performance appearing enhanced when combined with the A2DS2 score. Dysphagia and a large infarct volume emerged as potential risk factors for SAP. Conversely, within the context of our cohort, plasma levels of IL-6, CRP, and PCT did not demonstrate clear utility for the early prediction of SAP.

Frontiers in NeurologyVol. 17
Fujian Medical University (CN), Zhangzhou Municipal Hospital of Fujian Province (CN), First Affiliated Hospital of Fujian Medical University (CN)
Fujian Medical University
Good health and well-being
Openalex Percentile: Top 54%
Neuroinflammation and Neurodegeneration Mechanisms
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