The predictive value of circulating inflammatory and immune biomarkers for stroke-associated pneumonia following endovascular therapy in patients with acute anterior circulation large vessel occlusion infarction: a prospective cohort study
In this exploratory study, our findings suggest that mHLA-DR expression levels may indicate some predictive value for SAP development after EVT in ACLVO patients, with the predictive performance appearing enhanced when combined with the A2DS2 score. Dysphagia and a large infarct volume emerged as potential risk factors for SAP. Conversely, within the context of our cohort, plasma levels of IL-6, CRP, and PCT did not demonstrate clear utility for the early prediction of SAP.
Authors
- Lin Tian (ORCID: https://orcid.org/0000-0001-5314-4188)
- Zhuquan Hong
- Z Zhu
- Xiaorong Zhang (ORCID: https://orcid.org/0000-0003-2343-6811)
- Pingzhen LIN
- Quanlong Hong
- Biyu Wu
Institutions
- Fujian Medical University (CN)
- Zhangzhou Municipal Hospital of Fujian Province (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3389/fneur.2026.1764204
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fujian Medical University