Sex-specific association of visceral adiposity index with renal dysfunction in chinese type 2 diabetes: A cross-sectional study

Visceral adiposity index showed strong and consistent associations with renal dysfunction specifically in Chinese male T2DM patients, while female associations were primarily mediated through confounding pathways. These findings highlight critical sex-specific differences and support the integration of composite visceral adiposity indices into routine clinical assessment for male diabetic patients, emphasizing the necessity of population-specific and gender-tailored approaches in renal risk stratification.

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Publication Details

Journal
PLoS ONE
Published
2026-02-25
DOI
https://doi.org/10.1371/journal.pone.0343375
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
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0.00
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article

Sex-specific association of visceral adiposity index with renal dysfunction in chinese type 2 diabetes: A cross-sectional study

Bingyin Shi, Liu S, louyan Ma, Yu Niu et al.
PLoS ONE
Chronic Kidney Disease and Diabetes
article

Sex-specific association of visceral adiposity index with renal dysfunction in chinese type 2 diabetes: A cross-sectional study

Bingyin Shi, Liu S, louyan Ma, Yu Niu, Ting Qi, Ranran Ma
article en

Abstract

Visceral adiposity index showed strong and consistent associations with renal dysfunction specifically in Chinese male T2DM patients, while female associations were primarily mediated through confounding pathways. These findings highlight critical sex-specific differences and support the integration of composite visceral adiposity indices into routine clinical assessment for male diabetic patients, emphasizing the necessity of population-specific and gender-tailored approaches in renal risk stratification.

PLoS ONEVol. 21(2)
First Affiliated Hospital of Xi'an Jiaotong University (CN), First Hospital of Xi'an (CN)
Good health and well-being
Openalex Percentile: Top 50%
Chronic Kidney Disease and Diabetes
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