Rapid clearance of facial verruca plana with local hyperthermia treatment combined with topical interferon alpha-2b in 3 weeks: a case report

The combination of targeted local hyperthermia and topical interferon alpha-2b gel appears to be a safe, effective, and cosmetically favorable treatment for extensive facial verruca plana. This regimen harnesses both immunomodulatory and antiviral mechanisms to accelerate viral lesion clearance while preserving skin integrity. Further studies in larger cohorts are warranted to validate this approach.