Immunogenicity of Two Versus Three Doses of Hepatitis B Vaccine When Administered to Children Aged 2–18 Months: A Randomized Clinical Trial
The anamnestic response three years after two- (2, 12 months) and three-dose (2, 4, 18 months) hepatitis B vaccination schedules was similar. The heterologous two-dose schedule was more immunogenic and less reactogenic than the homologous two-dose schedule.
Authors
- C Quach
- J. Bestman-Smith
- Chantal Sauvageau (ORCID: https://orcid.org/0000-0002-4300-1658)
- M. Desjardins
- Koffi Barnabé Kegbevi
- Marie-Michelle Ursu
- Nicholas Brousseau
- Yossi Febriani
Institutions
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- Centre hospitalier universitaire de Québec (CA)
- Institut National de Santé Publique du Québec (CA)
- Centre hospitalier de l'Université Laval (CA)
- Centre Hospitalier de l’Université de Montréal (CA)
- Université Laval (CA)
- Université de Montréal (CA)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1093/infdis/jiag122
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00