Feasibility and efficacy of carotid-cavernous fistulas embolization with Onyx combined with coils: a systematic review and single-arm meta-analysis

Embolization of CCFs using Onyx combined with coils is a highly effective and safe treatment, yielding consistently high obliteration and symptomatic resolution rates. This approach appears especially promising for direct (type A) fistulas. Nevertheless, larger prospective studies are needed to establish its comparative efficacy across all CCF subtypes.

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Publication Details

Journal
Neurological Research
Published
2026-02-25
DOI
https://doi.org/10.1080/01616412.2026.2636851
Primary Topic
Vascular Malformations Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Feasibility and efficacy of carotid-cavernous fistulas embolization with Onyx combined with coils: a systematic review and single-arm meta-analysis

Lucas Pari Mitre, Gustavo Sousa Nolêto, Irving Gabriel Calisaya-Madariaga, Ricardo Fonseca Oliveira Suruagy Motta et al.
Neurological Research
Vascular Malformations Diagnosis and Treatment
article

Feasibility and efficacy of carotid-cavernous fistulas embolization with Onyx combined with coils: a systematic review and single-arm meta-analysis

Lucas Pari Mitre, Gustavo Sousa Nolêto, Irving Gabriel Calisaya-Madariaga, Ricardo Fonseca Oliveira Suruagy Motta, Marcelo Costa, Wilson Coelho Nogueira de Castro, Ocílio Ribeiro Gonçalves, Julia Oliveira Franco, Luiz Guilherme Silva Almeida
article en

Abstract

Embolization of CCFs using Onyx combined with coils is a highly effective and safe treatment, yielding consistently high obliteration and symptomatic resolution rates. This approach appears especially promising for direct (type A) fistulas. Nevertheless, larger prospective studies are needed to establish its comparative efficacy across all CCF subtypes.

Neurological Research
Pontifícia Universidade Católica do Paraná (BR), Wright State University (US), Universidad Peruana Cayetano Heredia (PE), Universidade Católica de Brasília (BR), Universidade Federal do Piauí (BR), Universidade Estadual do Piauí (BR), Southwestern Medical Center (US), Centro Universitário Cesmac (BR), Southwestern Medical Center (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 48%
Vascular Malformations Diagnosis and Treatment
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