Impact of the Unified Protocol on Attenuated Psychotic Symptoms, Cognitive Biases and Cognitive Insight in Patients at Ultra High Risk (UHR) for Psychosis: Secondary Results of a Pilot Randomized Controlled Trial

The UP intervention showed promising effects in reducing distress related to attenuated psychotic symptoms and cognitive biases, but not in improving cognitive insight. Given the small sample size, which fell below the initial target, and the pilot nature of the study, these findings should be interpreted with caution and considered preliminary until replicated in adequately powered trials.

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Publication Details

Journal
Journal of Clinical Psychology
Published
2026-02-24
DOI
https://doi.org/10.1002/jclp.70117
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
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article

Impact of the Unified Protocol on Attenuated Psychotic Symptoms, Cognitive Biases and Cognitive Insight in Patients at Ultra High Risk (UHR) for Psychosis: Secondary Results of a Pilot Randomized Controlled Trial

Victoria Florencia Centurión Espinosa, Jorge Enrique Avendaño Osma, Susana Araya, Sol Balsells et al.
Journal of Clinical Psychology
Schizophrenia research and treatment
article

Impact of the Unified Protocol on Attenuated Psychotic Symptoms, Cognitive Biases and Cognitive Insight in Patients at Ultra High Risk (UHR) for Psychosis: Secondary Results of a Pilot Randomized Controlled Trial

Victoria Florencia Centurión Espinosa, Jorge Enrique Avendaño Osma, Susana Araya, Sol Balsells, Raquel López-Carrilero, Paolo Fusar-Poli, Trinidad Peláez
article en

Abstract

The UP intervention showed promising effects in reducing distress related to attenuated psychotic symptoms and cognitive biases, but not in improving cognitive insight. Given the small sample size, which fell below the initial target, and the pilot nature of the study, these findings should be interpreted with caution and considered preliminary until replicated in adequately powered trials.

Journal of Clinical Psychology
King's College London (GB), South London and Maudsley NHS Foundation Trust (GB), University of Pavia (IT), Universidad de Zaragoza (ES), Centro de Investigación Biomédica en Red de Salud Mental (ES), Red de Investigación en Actividades Preventivas y Promoción de la Salud (ES), Sant Joan de Déu Research Foundation (ES), Parc Sanitari Sant Joan de Déu (ES), Instituto de Investigación Sanitaria Aragón (ES), Institut de Recerca Sant Joan de Déu, Ludwig-Maximilians-Universität München (DE)
Openalex Percentile: Top 48%
Schizophrenia research and treatment
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