The Role of Nontuberculous Mycobacteria in Patients With Cystic Fibrosis Advanced Lung Disease

NTM-positive CF patients were associated with a lower pre-transplant risk of death or transplantation. Post-transplant mortality was higher in NTM-positive patients, while no association between NTM infection and CLAD was observed. These findings indicate that favorable outcomes after lung transplantation are achievable in NTM-positive patients. Thus, NTM-infection should not be an absolute contraindication for lung transplantation, though careful individual assessment is essential due to the risk of serious complications.

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Publication Details

Journal
Transplant Infectious Disease
Published
2026-02-25
DOI
https://doi.org/10.1111/tid.70190
Primary Topic
Mycobacterium research and diagnosis
Type
article
Field-Weighted Citation Impact
0.00
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article

The Role of Nontuberculous Mycobacteria in Patients With Cystic Fibrosis Advanced Lung Disease

Zisis Balmpouzis, A. Koutsokera, Ribal Bou Mjahed, Oriol Josep Manuel et al.
Transplant Infectious Disease
Mycobacterium research and diagnosis
article

The Role of Nontuberculous Mycobacteria in Patients With Cystic Fibrosis Advanced Lung Disease

Zisis Balmpouzis, A. Koutsokera, Ribal Bou Mjahed, Oriol Josep Manuel, Nicolas Johannes Mueller, Shirin Barcikowski, Adrian Alonso
article en

Abstract

NTM-positive CF patients were associated with a lower pre-transplant risk of death or transplantation. Post-transplant mortality was higher in NTM-positive patients, while no association between NTM infection and CLAD was observed. These findings indicate that favorable outcomes after lung transplantation are achievable in NTM-positive patients. Thus, NTM-infection should not be an absolute contraindication for lung transplantation, though careful individual assessment is essential due to the risk of serious complications.

Transplant Infectious Disease
University of Zurich (CH), University Hospital of Zurich (CH), University of Lausanne (CH)
Good health and well-being
Openalex Percentile: Top 43%
Mycobacterium research and diagnosis
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