Nutritional and Phytochemical Profile and Potential Anticancer Benefits of Amazonian Exotic Fruits

The focus on natural compounds and their potential health benefits has gained considerable momentum in scientific research, particularly in the context of cancer prevention and treatment, a global issue that demands innovative approaches. Among natural sources, fruits from the Amazon rainforest have garnered attention for their rich nutritional profiles and bioactive compounds, which may provide therapeutic properties. This study aimed to compile scientific data found in the literature up to 2025 on the nutritional compounds, phytochemicals, and anticancer properties of selected fruits including murici (Byrsonima crassifolia and B verbascifolia), taperebá (Spondias mombin), camu-camu (Myrciaria dubia), bacuri (Platonia insignis), araçá-boi (Eugenia stipitata), tucumã (Astrocaryum aculeatum), and abricó (Mammea americana), highlighting the main mechanisms involved. These fruits have shown promising evidence of various anticancer actions, including antiproliferative, antigenotoxic, antimutagenic, antioxidant, antiangiogenic, antimetastatic, and anti-inflammatory effects. By elucidating the molecular mechanisms underlying these actions and synthesizing results from in vitro and in vivo studies, this research underscores the invaluable role of these Amazonian fruits as potent sources of bioactive compounds, offering new perspectives for advancing cancer treatment strategies.