Allogeneic Hematopoietic Stem Cell Transplantation for Children With Mixed Phenotype Acute Leukemia: A Single-Center Retrospective Study

The children with MPAL who received allo-HSCT after MRD-negative CR often had a favorable disease control. Compared with patients receiving conventional chemotherapy, pediatric patients who received allo-HSCT showed a significant improvement in OS, EFS, and CIR rates. Although the incidence of cGVHD was relatively high, most of them were assessed as mild with no significant impact on daily activities.