Diagnostic Performance of New Commercial Interferon-Gamma Release Assays for <i>Mycobacterium tuberculosis</i> Infection: An Updated Systematic Review and Meta-analysis
Two of the eight new tests reviewed showed promising accuracy and high agreement with WHO-endorsed IGRAs. The overall certainty of evidence remains low due to risk of bias and imprecision. High-quality, independent studies in diverse populations and settings are needed to inform future WHO recommendations for TB infection tests.
Authors
- Harjot Sidhu (ORCID: https://orcid.org/0009-0006-8413-9123)
- Lika Dwi Apriani
- Nazir Ismail
- Dick Menzies
- Alexei Korobitsyn
Institutions
- National Health Laboratory Service (ZA)
- McGill University Health Centre (CA)
- World Health Organization (CH)
- McGill University (CA)
- Padjadjaran University (ID)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2026-02-21
- DOI
- https://doi.org/10.1093/cid/ciag102
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00