Conservative management of cervical intraepithelial neoplasia grade 2 and immunohistochemical staining of p16 and Ki-67: Data from a Brazilian institution
CIN2 regression occurred in 76% of cases, with median times of approximately 12 months for regression and 32 months for progression. No statistically significant associations were detected between baseline characteristics, including biomarkers, and lesion regression in this exploratory study.
Authors
- Fábio Bastos Russomano (ORCID: https://orcid.org/0000-0001-7510-0485)
- Amanda Leal Ferreira (ORCID: https://orcid.org/0000-0001-8671-8918)
- Cecília Vianna De Andrade
- Yara Lúcia Mendes Furtado de Melo (ORCID: https://orcid.org/0000-0001-8280-6160)
- Saint Clair dos Santos Gomes Júnior
- Dione Corrêa Araújo Dock
- Elyzabeth Avvad Portari
- Nilma Valéria Ferreira Caldeira
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Instituto Federal do Rio de Janeiro (BR)
- Fundação Instituto de Pesca do Estado do Rio de Janeiro (BR)
- Fundação Oswaldo Cruz (BR)
- Universidade Federal do Estado do Rio de Janeiro (BR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1371/journal.pone.0342001
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00