Effect of a self-assembling peptide hydrogel on delayed bleeding following endoscopic sphincterotomy: Prospective pilot cohort study
SAPH is a simple, effective, and safe hemostatic option for treating EST-related hemorrhage and may be a promising first-line approach. This pilot study did not demonstrate a significant reduction in delayed bleeding, but absence of delayed bleeding in the SAPH group is noteworthy and suggests a potential preventive benefit. Thus, larger randomized controlled trials are warranted to validate these preliminary findings.
Authors
- Shinya Ashizuka (ORCID: https://orcid.org/0000-0003-2530-760X)
- Sadahiro Funakoshi (ORCID: https://orcid.org/0000-0002-4859-187X)
- FUMIHITO HIRAI
- Noriko Shiga
- Eiji Sadashima (ORCID: https://orcid.org/0000-0001-6716-3259)
- Tsutomu Iwasa (ORCID: https://orcid.org/0000-0001-5996-0602)
- Hiroto Ishikawa (ORCID: https://orcid.org/0000-0003-0760-7203)
- T Kitaguchi
- Kaori Hata
- Nobuaki Kuno (ORCID: https://orcid.org/0000-0003-3665-2177)
- Makoto Fukuyama
- Ryohei Nomaru (ORCID: https://orcid.org/0009-0005-1058-5166)
- So Imakiire (ORCID: https://orcid.org/0000-0002-7076-4335)
- Naoaki Tsuchiya
- Kei Nishioka
- Hiroki Matsuoka
- Yusuke Ishida
- Keisuke Matsumoto
- Takehiko Koga
Institutions
- Fukuoka University (JP)
- Saga-Ken Medical Centre Koseikan (JP)
- Yao Tokushukai General Hospital (JP)
- Fukui-ken Saiseikai Hospital (JP)
Publication Details
- Journal
- Endoscopy International Open
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1055/a-2803-3921
- Primary Topic
- Gallbladder and Bile Duct Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00