A Developmentally Informed Study of Sleep and Circadian Polygenic Scores in Adolescence

Results of this study suggest overlap in the genetic etiology of sleep and circadian phenotypes in adolescence and adulthood. This has importance for studies using genomic designs for causal inference about sleep and understanding of the extent to which genetic influences vary across the lifespan. Future research, including larger GWAS across developmental periods, is required to further understand genetic influences on sleep across the lifespan, as well as environmental influences on adolescent sleep disturbances.