A 10‐Year Retrospective Cohort Study of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis at the Royal Brisbane and Women's Hospital

SJS/TEN incidence matched published rates. Severity of SJS/TEN and mortality were correlated. Neither systemic immune suppression nor time taken to be admitted to the definitive tertiary centre correlated with mortality. Expert multidisciplinary care in the RBWH ICU and Burns Unit is likely to contribute to the excellent mortality outcomes found. Limitations of the study included its retrospective cohort design, that it was performed in a single centre, and the relatively small sample size leading to statistically insignificant findings. Our results should bolster growing data to improve understanding of this rare but serious condition.

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Publication Details

Journal
Australasian Journal of Dermatology
Published
2026-02-24
DOI
https://doi.org/10.1111/ajd.70076
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
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article

A 10‐Year Retrospective Cohort Study of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis at the Royal Brisbane and Women's Hospital

David Francis, Amanda Godbolt, Simon Yong‐Gee, Thomas Pagliaro et al.
Australasian Journal of Dermatology
Drug-Induced Adverse Reactions
article

A 10‐Year Retrospective Cohort Study of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis at the Royal Brisbane and Women's Hospital

David Francis, Amanda Godbolt, Simon Yong‐Gee, Thomas Pagliaro, G. G. Butler, Ivan Robertson
article en

Abstract

SJS/TEN incidence matched published rates. Severity of SJS/TEN and mortality were correlated. Neither systemic immune suppression nor time taken to be admitted to the definitive tertiary centre correlated with mortality. Expert multidisciplinary care in the RBWH ICU and Burns Unit is likely to contribute to the excellent mortality outcomes found. Limitations of the study included its retrospective cohort design, that it was performed in a single centre, and the relatively small sample size leading to statistically insignificant findings. Our results should bolster growing data to improve understanding of this rare but serious condition.

Australasian Journal of Dermatology
Royal Brisbane and Women's Hospital (AU)
Good health and well-being
Openalex Percentile: Top 43%
Drug-Induced Adverse Reactions
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