Effect of Different Sodium Hypochlorite Concentrations on Post Endodontic Pain: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Within the limitations of the present study, no significant differences in post-endodontic pain were found between high and low NaOCl concentrations. However, concentrations < 5% might be associated with less pain incidence. Further well-designed clinical trials with standardized methodologies are needed to provide more conclusive evidence.

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Publication Details

Journal
Clinical and Experimental Dental Research
Published
2026-02-24
DOI
https://doi.org/10.1002/cre2.70320
Primary Topic
Endodontics and Root Canal Treatments
Type
article
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0.00
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article

Effect of Different Sodium Hypochlorite Concentrations on Post Endodontic Pain: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Mariangela Cernera, Salvatore Scolavino, Romeo Patini, Flavia Iaculli et al.
Clinical and Experimental Dental Research
Endodontics and Root Canal Treatments
article

Effect of Different Sodium Hypochlorite Concentrations on Post Endodontic Pain: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Mariangela Cernera, Salvatore Scolavino, Romeo Patini, Flavia Iaculli, Kaligotla Apoorva Vasundhara, Kavalipurapu Venkata Teja, Gianrico Spagnuolo
article en

Abstract

Within the limitations of the present study, no significant differences in post-endodontic pain were found between high and low NaOCl concentrations. However, concentrations < 5% might be associated with less pain incidence. Further well-designed clinical trials with standardized methodologies are needed to provide more conclusive evidence.

Clinical and Experimental Dental ResearchVol. 12(2)
G Pulla Reddy Dental College & Hospital (IN), University of the Sacred Heart (JP), University of Naples Federico II (IT), Saveetha University (IN), Sapienza University of Rome (IT), Kamineni Institute of Dental Sciences (IN)
Good health and well-being
Openalex Percentile: Top 44%
Endodontics and Root Canal Treatments
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