Hypothalamic-pituitary deficiency after radiation in childhood cancer survivors is associated with rare variants in <i>TNS2</i>
TNS2 may contribute to radiation-induced HP deficiencies. With further validation, screening for TNS2 variants has potential to help identify individuals who would benefit from surveillance and intervention following HP-RT.
Authors
- T MERCHANT
- Yutaka Yasui (ORCID: https://orcid.org/0000-0002-7717-8638)
- Yadav Sapkota (ORCID: https://orcid.org/0000-0001-5943-9454)
- Asmita Neupane (ORCID: https://orcid.org/0000-0002-0405-655X)
- Carmen L. Wilson (ORCID: https://orcid.org/0000-0001-7636-065X)
- Tomoko Yoshida (ORCID: https://orcid.org/0000-0003-3340-7096)
- Fan Wang (ORCID: https://orcid.org/0000-0002-9869-9504)
- Ji Zhang (ORCID: https://orcid.org/0000-0001-9649-9608)
- Sogol Mostoufi-Moab
- Gregory T Armstrong
- Jian Wang
- Kirsten K Ness
- Huiqi Wang
- Sedigheh Mirzaei
- Melissa M Hudson
- Zhaoming Wang
- Wonjong Moon
- Angela Delaney
Institutions
- St. Jude Children's Research Hospital (US)
- University of South Florida (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1210/clinem/dgag080
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00