Prognostic significance of preoperative thyroid hormone sensitivity status for recurrence in papillary thyroid carcinoma

In conclusion, thyroid hormone resistance, indicated by elevated TSHI and TT4RI, represents an independent protective factor against recurrence in PTC. The integration of these indices significantly improves recurrence prediction, with their combination offering superior discriminative ability, highlighting their collective utility as clinically relevant biomarkers for optimizing postoperative surveillance and management strategies in PTC.

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Publication Details

Journal
The Oncologist
Published
2026-02-24
DOI
https://doi.org/10.1093/oncolo/oyag044
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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Prognostic significance of preoperative thyroid hormone sensitivity status for recurrence in papillary thyroid carcinoma

Jingting Li, Yishen Zhao, Canxiao Li, Rui Du et al.
The Oncologist
Thyroid Cancer Diagnosis and Treatment
article

Prognostic significance of preoperative thyroid hormone sensitivity status for recurrence in papillary thyroid carcinoma

Jingting Li, Yishen Zhao, Canxiao Li, Rui Du, Daqi Zhang, Shijie Li, Nan Liang, Yantao Fu, Hui Sun, Fang Li, Le Zhou
article en

Abstract

In conclusion, thyroid hormone resistance, indicated by elevated TSHI and TT4RI, represents an independent protective factor against recurrence in PTC. The integration of these indices significantly improves recurrence prediction, with their combination offering superior discriminative ability, highlighting their collective utility as clinically relevant biomarkers for optimizing postoperative surveillance and management strategies in PTC.

The OncologistVol. 31(4)
Union Hospital (CN)
Reduced inequalities
Openalex Percentile: Top 45%
Thyroid Cancer Diagnosis and Treatment
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