Medical Cannabis Use in France: An Observational Safety Study Based on the RECANN Registry and the Pharmacovigilance/Addictovigilance System From 2021 to 2024

During the experimentation, 3% of patients treated with MC experienced at least one serious ADR. The safety profile was dominated by neurological, gastrointestinal, and psychiatric ADRs. Only one case of MC misuse was identified with inflorescences. This study is observational and non-comparative and cannot provide a comprehensive assessment of the risk associated with MC use.

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Publication Details

Journal
Fundamental and Clinical Pharmacology
Published
2026-02-24
DOI
https://doi.org/10.1111/fcp.70074
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
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article

Medical Cannabis Use in France: An Observational Safety Study Based on the RECANN Registry and the Pharmacovigilance/Addictovigilance System From 2021 to 2024

Basile Chrétien, Sophie Fédrizzi, Véronique Ferey, Louise Gaboriau et al.
Fundamental and Clinical Pharmacology
Cannabis and Cannabinoid Research
article

Medical Cannabis Use in France: An Observational Safety Study Based on the RECANN Registry and the Pharmacovigilance/Addictovigilance System From 2021 to 2024

Basile Chrétien, Sophie Fédrizzi, Véronique Ferey, Louise Gaboriau, Emilie Monzon, Nicolas Authier, Marine Auffret, Cécile Chevallier, Anne Batisse, Chouki Chenaf, Nathalie Richard
article en

Abstract

During the experimentation, 3% of patients treated with MC experienced at least one serious ADR. The safety profile was dominated by neurological, gastrointestinal, and psychiatric ADRs. Only one case of MC misuse was identified with inflorescences. This study is observational and non-comparative and cannot provide a comprehensive assessment of the risk associated with MC use.

Fundamental and Clinical PharmacologyVol. 40(2)
Université Claude Bernard Lyon 1 (FR), Inserm (FR), Centre Hospitalier Universitaire de Lille (FR), Assistance Publique – Hôpitaux de Paris (FR), Hospices Civils de Lyon (FR), Groupe de Recherche sur l'Alcool et les Pharmacodépendances (FR), Agence Nationale de Sécurité du Médicament et des Produits de Santé (FR), Observatoire de Physique du Globe de Clermont-Ferrand (FR), Centre Hospitalier Universitaire de Caen Normandie (FR), Centre Hospitalier Universitaire de Clermont-Ferrand (FR), Laboratoire de Biométrie et Biologie Evolutive (FR), Université de Caen Normandie (FR)
Good health and well-being
Openalex Percentile: Top 43%
Cannabis and Cannabinoid Research
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