Prevalence of anti-NMDA receptor antibodies among adult patients presenting with first-episode psychosis in Hong Kong

Studies on the presence of anti-NMDA receptor antibodies were done primarily on the European population. This study investigates the prevalence of anti-NMDA antibodies among adult patients presenting with first-onset psychosis in an acute medical setting in the predominantly Chinese population of Hong Kong (n = 109), and our results suggest that such prevalence is low in this population (1.8%), especially among patients with primary psychotic disorders (0%). Further studies are needed to explore the ethnic variation in anti-NMDA receptor positivity.

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Publication Details

Journal
Schizophrenia
Published
2026-02-25
DOI
https://doi.org/10.1038/s41537-026-00741-2
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Prevalence of anti-NMDA receptor antibodies among adult patients presenting with first-episode psychosis in Hong Kong

Steven Wai Ho Chau, Chen‐Fuh Lam, Howan H. W. Leung, Joseph CH Choi et al.
Schizophrenia
Autoimmune Neurological Disorders and Treatments
article

Prevalence of anti-NMDA receptor antibodies among adult patients presenting with first-episode psychosis in Hong Kong

Steven Wai Ho Chau, Chen‐Fuh Lam, Howan H. W. Leung, Joseph CH Choi, Matthew PM Yu
article en

Abstract

Studies on the presence of anti-NMDA receptor antibodies were done primarily on the European population. This study investigates the prevalence of anti-NMDA antibodies among adult patients presenting with first-onset psychosis in an acute medical setting in the predominantly Chinese population of Hong Kong (n = 109), and our results suggest that such prevalence is low in this population (1.8%), especially among patients with primary psychotic disorders (0%). Further studies are needed to explore the ethnic variation in anti-NMDA receptor positivity.

Schizophrenia
Chinese University of Hong Kong (HK), Prince of Wales Hospital (CN)
Openalex Percentile: Top 48%
Autoimmune Neurological Disorders and Treatments
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