Longitudinal Changes in Corneal Epithelial Thickness After FS-LASIK, KLEx, and Transepithelial PRK: A Systematic Review and Meta-Analysis

Distinct epithelial remodeling patterns were observed: rapid, early thickening and stabilization with FS-LASIK and KLEx versus delayed regeneration with tPRK. Baseline SE and programmed OZ are predictors of corneal epithelial thickness changes, suggesting procedure-specific remodeling profiles that may support future refinement of refractive planning.

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Publication Details

Journal
Journal of Cataract & Refractive Surgery
Published
2026-02-25
DOI
https://doi.org/10.1097/j.jcrs.0000000000001924
Primary Topic
Corneal surgery and disorders
Type
article
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article

Longitudinal Changes in Corneal Epithelial Thickness After FS-LASIK, KLEx, and Transepithelial PRK: A Systematic Review and Meta-Analysis

J R Y Wang, Tsung-Hsien Tsai, Louis K. Chang, Jui‐Hung Hsu et al.
Journal of Cataract & Refractive Surgery
Corneal surgery and disorders
article

Longitudinal Changes in Corneal Epithelial Thickness After FS-LASIK, KLEx, and Transepithelial PRK: A Systematic Review and Meta-Analysis

J R Y Wang, Tsung-Hsien Tsai, Louis K. Chang, Jui‐Hung Hsu, Chi-Chin Su
article en

Abstract

Distinct epithelial remodeling patterns were observed: rapid, early thickening and stabilization with FS-LASIK and KLEx versus delayed regeneration with tPRK. Baseline SE and programmed OZ are predictors of corneal epithelial thickness changes, suggesting procedure-specific remodeling profiles that may support future refinement of refractive planning.

Journal of Cataract & Refractive Surgery
Chang Gung University (TW), Chang Gung Memorial Hospital (TW), Keelung Chang Gung Memorial Hospital (TW), Buddhist Tzu Chi General Hospital (TW), Hualien Tzu Chi Medical Center (TW)
Partnerships for the goals
Openalex Percentile: Top 44%
Corneal surgery and disorders
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