CD14 plays a critical role in pain and inflammation across multiple models of post‐traumatic osteoarthritis
Our results strongly support that targeting synovial and fat pad inflammation through blockade of CD14 can safely ameliorate OA pain and disability after a pre-disposing injury.
Authors
- Sung Yeon Kim
- Anna E. Rapp (ORCID: https://orcid.org/0000-0001-5122-765X)
- L. M. Murphy
- Sanique South
- Baofeng Hu (ORCID: https://orcid.org/0009-0003-2954-9056)
- Timothy M. Griffin (ORCID: https://orcid.org/0000-0001-8840-9940)
- Hung Li-Yin
- Joshua F. Baker (ORCID: https://orcid.org/0000-0003-0170-028X)
- Anne-Marie Malfait
- Kate Sharp
- De'Broski Herbert
- Shingo Ishihara
- Carla R Scanzello
- Natalie S Adamczyk
- Robert L Mauck
- Kevin G Burt
- Cheng Zhou
- Vu Nguyen
- Rachel E Miller
Institutions
- Rush University Medical Center (US)
- University of Oregon (US)
- Hospital of the University of Pennsylvania (US)
- Veterans Health Administration (US)
- Oklahoma Medical Research Foundation (US)
- Oklahoma City VA Medical Center (US)
- Philadelphia VA Medical Center (US)
- University of Pennsylvania (US)
- Philadelphia University (US)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1002/art.70100
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00