Iopanoic acid rapidly restores euthyroidism in refractory thyrotoxicosis pre-thyroidectomy: a retrospective study
IOPA is a safe and effective agent for controlling biochemical thyrotoxicosis in preparation for thyroidectomy, including disease refractory to conventional medication. Highly pure, laboratory-grade iopanoic acid that is approved for human use is now available in the UK; consideration should be given to more widespread use for emergency treatment of life-threatening hyperthyroidism.
Authors
- Denise Tapa
- Brian Fish
- Christine Newman (ORCID: https://orcid.org/0000-0003-2387-4109)
- David Halsall (ORCID: https://orcid.org/0000-0002-2301-6449)
- Susan Oddy
- Piyush Jani
- Diana Wood
- Greta Lyons
- Carla Moran
- Muhammed Saqlain
- Isra Ahmed Mohammed
- Nadia Schoenmakers
- Krishna Chatterjee
Institutions
- University of Cambridge (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Wellcome/MRC Institute of Metabolic Science (GB)
- Wellcome Trust (GB)
Publication Details
- Journal
- European Thyroid Journal
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1530/etj-25-0350
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- National Institute for Health and Care Research
- NIHR Cambridge Biomedical Research Centre