Randomized controlled clinical trial of the impact of combined application of rhamnosus probiotics and oral nystatin on the colonization of intestinal Candida albicans in low birth weight neonates <2,500 grams

The concurrent use of Rhamnosus probiotics and oral Nystatin can lead to a reduction of positive <i>C. albicans</i> stool culture results, average time for certain variables such as the onset of nutrition, time to reach 100 ml/kg of milk intake per day, NPO days, total NPO time during hospitalization, episodes of intolerance until discharge, and duration of hospitalization in infants weighing <2,500 grams. Hence, their simultaneous administration is recommended for these neonates.

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Publication Details

Journal
PubMed
Published
2026-02-25
DOI
https://doi.org/10.3205/dgkh000632
Primary Topic
Probiotics and Fermented Foods
Type
article
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article

Randomized controlled clinical trial of the impact of combined application of rhamnosus probiotics and oral nystatin on the colonization of intestinal Candida albicans in low birth weight neonates <2,500 grams

Mazyar Vakiliamini, R Chegenelorestani, Hajar Motamed, Majid Rezaei et al.
PubMed
Probiotics and Fermented Foods
article

Randomized controlled clinical trial of the impact of combined application of rhamnosus probiotics and oral nystatin on the colonization of intestinal Candida albicans in low birth weight neonates <2,500 grams

Mazyar Vakiliamini, R Chegenelorestani, Hajar Motamed, Majid Rezaei, Mosayeb Rostamian, Samira Zarei, Pourya Mohammadi, Reza Habibi, Farzad Mashreghi, Fatemeh Rezaeeniya
article en

Abstract

The concurrent use of Rhamnosus probiotics and oral Nystatin can lead to a reduction of positive <i>C. albicans</i> stool culture results, average time for certain variables such as the onset of nutrition, time to reach 100 ml/kg of milk intake per day, NPO days, total NPO time during hospitalization, episodes of intolerance until discharge, and duration of hospitalization in infants weighing <2,500 grams. Hence, their simultaneous administration is recommended for these neonates.

PubMedVol. 21
Lorestan University of Medical Sciences (IR), Kermanshah University of Medical Sciences (IR), Tabaran Institute of Higher Education (IR), Bushehr University of Medical Sciences (IR), Qazvin University of Medical Sciences (IR)
Zero hunger
Openalex Percentile: Top 44%
Probiotics and Fermented Foods
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