A randomized, double-blind, crossover study of acute low-level night-time road traffic noise: effects on vascular function, sleep, and proteomic signatures in healthy adults
Acute exposure to night-time road traffic noise leads to measurable changes in cardiovascular health parameters in healthy adults. These effects were linked to activation of molecular pathways of immune signalling. Plasma proteome changes were correlated to FMD changes (responders vs. non-responders), highlighting interindividual biological susceptibility to noise.
Authors
- Irene Schmidtmann (ORCID: https://orcid.org/0000-0001-8743-6752)
- Johannes Herzog (ORCID: https://orcid.org/0000-0002-7822-2522)
- Paul Stamm
- Marin Kuntić (ORCID: https://orcid.org/0000-0003-2435-851X)
- Andreas Daiber (ORCID: https://orcid.org/0000-0002-2769-0094)
- Frank P. Schmidt (ORCID: https://orcid.org/0000-0002-4241-7037)
- Volker H. Schmitt (ORCID: https://orcid.org/0000-0001-5070-7280)
- Lukas Hobohm (ORCID: https://orcid.org/0000-0002-4312-0366)
- Patrick Foos
- Christina Große-Dresselhaus
- Jonas Hübner
- Mir Abolfazl Ostad
- P H I L I P Lurz
- T Köck
- Philipp S. Wild
- Alexander von Kriegsheim
- Thomas Münzel
- Karsten Keller
- Martin Röösli
- Omar Hahad
- Mette Sørensen
Institutions
- Roskilde University (DK)
- Swiss Tropical and Public Health Institute (CH)
- University of Basel (CH)
- Johannes Gutenberg University Mainz (DE)
- Edinburgh Cancer Research (GB)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Universitätsklinikum Krems (AT)
- Klinikum Mutterhaus der Borromäerinnen (DE)
- German Centre for Cardiovascular Research (DE)
- Danish Cancer Society (DK)
Publication Details
- Journal
- Cardiovascular Research
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1093/cvr/cvag028
- Primary Topic
- Noise Effects and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00