Tecovirimat for the Treatment of Mpox
This trial showed no evidence that tecovirimat therapy shortened the time to clinical resolution, reduced pain, or increased viral clearance among adults with clade II mpox. (Funded by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health; STOMP/A5418 ClinicalTrials.gov number, NCT05534984.).
Authors
- Sharon Nachman (ORCID: https://orcid.org/0000-0002-3419-9471)
- Lu Zheng (ORCID: https://orcid.org/0000-0002-3636-2631)
- C. McCarthy
- Cheryl L. Day
- Matthew M. Hamill (ORCID: https://orcid.org/0000-0002-1277-819X)
- Karen P. Acker (ORCID: https://orcid.org/0000-0001-6559-5517)
- Kieron Seymour Leslie (ORCID: https://orcid.org/0000-0003-3504-2633)
- Kristina M. Brooks (ORCID: https://orcid.org/0000-0002-3832-8699)
- Kathie G. Ferbas (ORCID: https://orcid.org/0009-0005-8861-2240)
- Grace M. Aldrovandi (ORCID: https://orcid.org/0000-0003-1604-9637)
- Jonathan Berardi (ORCID: https://orcid.org/0000-0003-3415-2056)
- Lara A. Hosey
- R. Gandhi
- Joe J Eron
- Timothy J. Wilkin
- Arzhang Cyrus Javan
- Rachel A. Bender Ignacio
- William A. Fischer
- Robert Bolan
- Juan Sierra Madero
- Pooja T. Saha
- Anne F. Luetkemeyer
Institutions
- Rutgers, The State University of New Jersey (US)
- University of North Carolina at Chapel Hill (US)
- National Institutes of Health (US)
- Johns Hopkins University (US)
- Emory University (US)
- University of California, Los Angeles (US)
- University of California, San Francisco (US)
- University of Washington (US)
- Cornell University (US)
- Columbia University Irving Medical Center (US)
- Johns Hopkins Medicine (US)
- University of Washington Medical Center (US)
- Los Angeles LGBT Center (US)
- University of California San Diego (US)
- Massachusetts General Hospital (US)
- The Coordinating Center (US)
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Cancer Research And Biostatistics (US)
- National Institute of Allergy and Infectious Diseases (US)
- Weill Cornell Medical College in Qatar (QA)
- Rutgers New Jersey Medical School (US)
- University of Colorado Anschutz Medical Campus (US)
- Stony Brook University (US)
- University of Montana (US)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1056/nejmoa2506495
- Citations
- 2
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 54.40