Optical coherence tomography-derived coronary vessel wall abnormalities in adults long after Kawasaki disease

The present study showed that CALs in adults long after acute KD with severe coronary involvement are associated with OCT-derived vessel wall abnormalities, which are correlated with luminal lesions and MDCT-detected calcified plaques. Although these results do not demonstrate causality and may not be generalizable to milder cases, they warrant further studies to optimize screening and monitoring of adult KD-related coronary sequelae.

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Publication Details

Journal
PLoS ONE
Published
2026-02-25
DOI
https://doi.org/10.1371/journal.pone.0342987
Primary Topic
Kawasaki Disease and Coronary Complications
Type
article
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Optical coherence tomography-derived coronary vessel wall abnormalities in adults long after Kawasaki disease

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article en

Abstract

The present study showed that CALs in adults long after acute KD with severe coronary involvement are associated with OCT-derived vessel wall abnormalities, which are correlated with luminal lesions and MDCT-detected calcified plaques. Although these results do not demonstrate causality and may not be generalizable to milder cases, they warrant further studies to optimize screening and monitoring of adult KD-related coronary sequelae.

PLoS ONEVol. 21(2)
Mie University (JP), Toyohashi Heart Center (JP), Saiseikai Matsuyama Hospital (JP)
Good health and well-being
Openalex Percentile: Top 44%
Kawasaki Disease and Coronary Complications
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