The effects of prophylactic use of paracetamol on body temperature and blood pressure in elderly patients with acute stroke: Data from the PRECIOUS trial
Prophylactic use of paracetamol resulted in a modest reduction in mean body temperature and almost halved the rate of subfebrile temperatures or fever at 24 hours after stroke, but had no effect on blood pressure.
Authors
- Janika Kõrv
- Hendrik Reinink (ORCID: https://orcid.org/0000-0002-5047-9174)
- Wouter M. Sluis (ORCID: https://orcid.org/0000-0003-3057-2010)
- Jesse Dawson
- Alfonso Ciccone
- Anne Hege Aamodt
- Iwona Kurkowska-Jastrzebska
- Götz Thomalla
- Diederik van de Beek
- for the PRECIOUS investigators
- Milani Deb-Chatterji
- Jeroen C. de Jonge
- Philip Bath
- H Bart van der Worp
- George Ntaios
Institutions
- Oslo University Hospital (NO)
- University of Nottingham (GB)
- Universität Hamburg (DE)
- Norwegian University of Science and Technology (NO)
- Aristotle University of Thessaloniki (GR)
- University Medical Center Utrecht (NL)
- St. Antonius Ziekenhuis (NL)
- Amsterdam Neuroscience (NL)
- University Medical Center Hamburg-Eppendorf (DE)
- University Hospital Schleswig-Holstein (DE)
- Institute of Psychiatry and Neurology (PL)
- Spaarne Gasthuis (NL)
- University of Tartu (EE)
- University of Glasgow (GB)
- University of Lübeck (DE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1371/journal.pone.0342937
- Primary Topic
- Thermal Regulation in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00