Endocrinopathies and Their Recovery in a 20‐Year Cohort Study of People With Heroin Dependence
Opioid-induced endocrine suppression appears reversible with sustained opioid abstinence. Higher methadone dose, male sex, and depression were associated with hypogonadism. Despite frequent healthcare contact, patients remained undiagnosed, highlighting a gap in clinical awareness of opioid-associated endocrinopathies and the need for routine screening in opioid agonist treatment settings.
Authors
- Katherine L. Mills (ORCID: https://orcid.org/0000-0002-9714-1832)
- Maree Teesson (ORCID: https://orcid.org/0000-0003-0450-1999)
- Christina Marel (ORCID: https://orcid.org/0000-0002-1371-6986)
- SM Twigg
- Paul Haber (ORCID: https://orcid.org/0000-0001-8915-8872)
- Chris Tremonti
Institutions
- The University of Sydney (AU)
- Royal Prince Alfred Hospital (AU)
- St Vincent's Hospital Sydney (AU)
Publication Details
- Journal
- Clinical Endocrinology
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1111/cen.70109
- Primary Topic
- Opioid Use Disorder Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00