Contribution of rare variation to degenerative orthopedic diseases
One established osteoporosis gene (<i>LRP5</i>) and two other DODs genes (<i>TET2</i> and <i>SMAD6</i>) were identified using gene collapsing analyses. Only a small number of genes reached the chosen significance threshold under the current phenotype definitions and analytic framework.
Authors
- Christina Lind‐Halldén
- Eric Manderstedt (ORCID: https://orcid.org/0000-0002-8984-9697)
- Christian Anker-Hansen (ORCID: https://orcid.org/0009-0002-8603-4254)
- Christer Halldén
- Bengt Zöller
Institutions
- Skåne University Hospital (SE)
Publication Details
- Journal
- Osteoarthritis and Cartilage Open
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1016/j.ocarto.2026.100767
- Primary Topic
- Dermatological and Skeletal Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00