Predictive modeling of treatment-related thyroid dysfunction and prognostic implication in advanced nasopharyngeal carcinoma with PD-1 inhibitors
This study identifies trTD as a common event associated with improved survival in advanced NPC patients treated with PD-1 inhibitors. A predictive nomogram and early TSH elevation provide valuable tools for risk stratification and personalized immunotherapy monitoring.
Authors
- Mohammed Ali Warsi
- Peidong Ou
- Yong Li (ORCID: https://orcid.org/0000-0003-4038-0493)
- Chaoying Lin
- Cuibo Lin (ORCID: https://orcid.org/0009-0006-9421-9418)
- H. H. Zhang
- Ronghui Chen
- Yubin Hu
- Xinyi Hong
Institutions
- Xiamen University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- The Oncologist
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1093/oncolo/oyag066
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00