Mechanistic insights into triclosan-induced hepatotoxicity: A network toxicology and molecular docking approach
The potential targets and molecular mechanisms of triclosan (TCS) induced liver injury were investigated, and 6 key targets and 5 pathways were identified, providing a new paradigm for evaluating the health risks caused by environmental pollutants.
Authors
- Zhuote Tu
- Zhaocheng Zhuang
- Fuzhi Liu
- Yangjia Chen
- Yanyan Zhao
- Yuan Su
- Jingwen Wang
- Dandan Zhu
Institutions
- Quanzhou Normal University (CN)
- Quzhou College of Technology (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1371/journal.pone.0333244
- Primary Topic
- Antimicrobial agents and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00