High normal parathyroid hormone and cardiovascular and total mortality: sex and age disparities in the ELSA-Brasil study
In this large, community-based cohort, PTH levels at the upper end of the reference range were associated with greater CV and all-cause mortality. The excess CV risk was restricted to females and younger adults, suggesting that PTH may serve as an early, sex-sensitive biomarker of cardiometabolic risk.
Authors
- Ana Cláudia Latronico (ORCID: https://orcid.org/0000-0001-6782-693X)
- Paulo A. Lotufo (ORCID: https://orcid.org/0000-0002-4856-8450)
- Vinícius F. Calsavara (ORCID: https://orcid.org/0000-0003-2332-5863)
- Eduardo Z Kawahara (ORCID: https://orcid.org/0009-0002-8054-2098)
- Isabela M. Bensenor
- Madson Quriroz Almeida
- Gustavo H Mori (ORCID: https://orcid.org/0000-0003-3547-6781)
- Jessica Okubo
Institutions
- Cedars-Sinai Medical Center (US)
- Instituto do Câncer do Estado de São Paulo (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2026-02-21
- DOI
- https://doi.org/10.1210/clinem/dgag076
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00