Risperidone-ISM <sup>®</sup> effectiveness and tolerability in acute schizophrenia patients hospitalised due to a relapse: results from an international, prospective, non-interventional evaluation (RESHAPE study)
Risperidone-ISM<sup>®</sup> demonstrated rapid and sustained effectiveness, functional improvement, and favourable tolerability, enabling early stabilisation and discharge. Adding another antipsychotic provided no additional benefits. Results support Risperidone-ISM<sup>®</sup> for treating acute schizophrenia relapse in real-world settings.
Authors
- MIQUEL BERNARDO
- Montserrat Caballero
- Javier Martínez (ORCID: https://orcid.org/0000-0001-6314-4480)
- Luiz Dratcu (ORCID: https://orcid.org/0000-0002-5888-4991)
- Lourdes Anta Carabias
- Daniel Schöttle (ORCID: https://orcid.org/0000-0002-8589-727X)
- H.-J. Assion
- Saeed Ahmad Saeedi Mudassir Farooq
- Joaquim Gago (ORCID: https://orcid.org/0000-0003-3525-1574)
- Stephan Heres (ORCID: https://orcid.org/0000-0002-1351-003X)
- Serafino De Giorgi
- Nuno Gonçalo Gomes Fernandes Madeira (ORCID: https://orcid.org/0000-0001-5009-8841)
- Savino Dimalta
- Rosa Molina
- Sofia Pappa
- Miquel Bioque
- Henrik Rohner
- Sheila Sánchez-García
- María Augusta Vieira Coelho
- Carmen Núñez Sande
- Thomas Messer
- Steffi Langner-Timm
- Peter Falkai
- Ana González-Pinto
- Christopher Landry
- Emilio Fernández-Egea
- Randi Susanne Göldner
- Christoph U. Correll
- Antonio Vita
- Giuseppe Maina
- Maximilian Gahr
Institutions
- Universidad Complutense de Madrid (ES)
- Universität Hamburg (DE)
- Universidade do Porto (PT)
- South London and Maudsley NHS Foundation Trust (GB)
- University of Cambridge (GB)
- University Hospital Bonn (DE)
- University Hospital Complex Of Vigo (ES)
- Hospital de São João (PT)
- Research Institute Hospital 12 de Octubre (ES)
- Laboratorios Farmaceúticos Rovi (Spain) (ES)
- ASL Roma (IT)
- Isar-Amper-Klinikum München-Ost (DE)
- Fundación Hospital Manacor (ES)
- Donald & Barbara Zucker School of Medicine at Hofstra/Northwell (US)
- University Medical Center Hamburg-Eppendorf (DE)
- Hospital Universitario Araba (ES)
- Vivantes Klinikum (DE)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- Nova Medical (United States) (US)
- Hospital Clínic de Barcelona (ES)
- Azienda Unita' Sanitaria Locale di Parma (IT)
- Centro Hospitalar de Lisboa Ocidental (PT)
- Klinik für Psychosomatik (DE)
- Krankenhaus Bethanien (DE)
- Landschaftsverband Westfalen-Lippe (DE)
- Cambridgeshire and Peterborough NHS Foundation Trust (GB)
- Connecticut Department of Mental Health and Addiction Services (US)
- Hospital Universitario Lucus Augusti (ES)
- Klinik und Poliklinik für Psychiatrie und Psychotherapie (DE)
- Ospedale San Luigi Gonzaga (IT)
- West London Mental Health NHS Trust (GB)
- Azienda Sanitaria Locale Roma 3 (IT)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Medical Research Network (US)
- Zucker Hillside Hospital (US)
- Imperial College London (GB)
- Keele University (GB)
- Escola Superior de Enfermagem de Coimbra (PT)
- Universitat de Barcelona (ES)
- University of Coimbra (PT)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- The World Journal of Biological Psychiatry
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1080/15622975.2026.2628198
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00