Clinical impact of chronic pulmonary aspergillosis in patients with pulmonary nontuberculous mycobacterial disease and colonization: a multicentre prospective cohort study

These findings indicate that approximately one-third of pulmonary NTM isolation patients have elevated <i>Aspergillus</i>-specific IgG, about 10% develop CPA, and CPA development is associated with poor survival. Therefore, longitudinal monitoring of Aspergillus-specific IgG is warranted to facilitate early detection and management of CPA in patients with pulmonary NTM isolation.