Sex, age, and racial/ethnic disparities in hyperuricemia prevalence and risk factors among U.S. adults: An analysis of NHANES 2007–2018 data

Hyperuricemia remains highly prevalent in the U.S., with notable disparities by sex, age, and race/ethnicity. Older women bear a particularly high burden, partly due to obesity, renal dysfunction, and diuretic use. Incorporating medication use into analyses strengthens the evidence for sex-specific risk profiles. These findings highlight the importance of considering targeted screening and prevention strategies in specific high-risk groups, such as older women and patients receiving diuretics.

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Publication Details

Journal
PLoS ONE
Published
2026-02-25
DOI
https://doi.org/10.1371/journal.pone.0337714
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
0.00

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article

Sex, age, and racial/ethnic disparities in hyperuricemia prevalence and risk factors among U.S. adults: An analysis of NHANES 2007–2018 data

Ting Long, Yadan Zou, Zhongxing Zhao, Yanfeng Zhang et al.
PLoS ONE
Gout, Hyperuricemia, Uric Acid
article

Sex, age, and racial/ethnic disparities in hyperuricemia prevalence and risk factors among U.S. adults: An analysis of NHANES 2007–2018 data

Ting Long, Yadan Zou, Zhongxing Zhao, Yanfeng Zhang, Sheng-Guang Li, Jing Xu, Ruohan Yu, Ji Li, Lina Zhang, Jing Jing Zhang
article en

Abstract

Hyperuricemia remains highly prevalent in the U.S., with notable disparities by sex, age, and race/ethnicity. Older women bear a particularly high burden, partly due to obesity, renal dysfunction, and diuretic use. Incorporating medication use into analyses strengthens the evidence for sex-specific risk profiles. These findings highlight the importance of considering targeted screening and prevention strategies in specific high-risk groups, such as older women and patients receiving diuretics.

PLoS ONEVol. 21(2)
Shenyang Medical College (CN), Peking University (CN), Peking University International Hospital (CN)
General Hospital of People’s Liberation Army, Centers for Disease Control and Prevention
Zero hunger
Openalex Percentile: Top 51%
Gout, Hyperuricemia, Uric Acid
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