Optimizing Haploidentical Donor Selection for Pediatric Hematopoietic Cell Transplant

Donors <18 years are associated with reduced aGVHD and cGVHD, whereas maternal donors are associated with increased cGVHD risk. For pediatric patients, sibling donors should be considered to reduce GVHD.

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Publication Details

Journal
Journal of Clinical Oncology
Published
2026-02-25
DOI
https://doi.org/10.1200/jco-25-01591
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Optimizing Haploidentical Donor Selection for Pediatric Hematopoietic Cell Transplant

Rishikesh Chavan, Erin Doherty, Nicole Liberio, Heather J. Symons et al.
Journal of Clinical Oncology
Hematopoietic Stem Cell Transplantation
article

Optimizing Haploidentical Donor Selection for Pediatric Hematopoietic Cell Transplant

Rishikesh Chavan, Erin Doherty, Nicole Liberio, Heather J. Symons, Mariam Allbee-Johnson, Sandhya Kharbanda, Rachel Phelan, Christine L. Phillips, Parinda A. Mehta, Kristin Page, Neena Kapoor, Javier Bolaños-Meade, Kirk R. Schultz, Christopher C. Dvorak, Akshay Sharma, Muna Qayed, Amanda E. Lipsitt, Bronwen E. Shaw, Larisa Broglie, Amy Moskop
article en

Abstract

Donors <18 years are associated with reduced aGVHD and cGVHD, whereas maternal donors are associated with increased cGVHD risk. For pediatric patients, sibling donors should be considered to reduce GVHD.

Journal of Clinical Oncology
Cincinnati Children's Hospital Medical Center (US), Children's Hospital of Orange County (US), St. Jude Children's Research Hospital (US), Children's Hospital of Los Angeles (US), University of British Columbia (CA), Johns Hopkins University (US), Emory University (US), Baylor College of Medicine (US), Medical College of Wisconsin (US), Johns Hopkins Medicine (US), Methodist Children’s Hospital (US), UCSF Benioff Children's Hospital (US), Children's Healthcare of Atlanta (US), Texas Children's Hospital (US), BC Children's Hospital (CA), Sidney Kimmel Comprehensive Cancer Center (US)
Good health and well-being
Openalex Percentile: Top 43%
Hematopoietic Stem Cell Transplantation
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