Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions

It is evident that reducing neuroinflammation is an important component of reducing brain tissue loss and functional impairments after stroke. A combination of therapies may be more effective for stroke-affected patients. This could include reducing neuroinflammation through immune therapies, in combination with some pharmaceuticals specific to the patient's needs. Furthermore, sex differences are highly prevalent in ischemic stroke outcomes. These differences can inform us of the best sex-specific interventions, treatments, or techniques that should be used in healthcare to ensure lower mortality rates and higher quality of life for all. Therapeutic development for ischemic stroke is needed, and this review highlights that targeting the immune system could lead to better outcomes for patients.

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Publication Details

Journal
Medical Sciences
Published
2026-02-25
DOI
https://doi.org/10.3390/medsci14010111
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions

Lauren Hurley, Kasey Pull, Riley McCabe, Nafisa M. Jadavji
Medical Sciences
Neuroinflammation and Neurodegeneration Mechanisms
article

Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions

Lauren Hurley, Kasey Pull, Riley McCabe, Nafisa M. Jadavji
article en

Abstract

It is evident that reducing neuroinflammation is an important component of reducing brain tissue loss and functional impairments after stroke. A combination of therapies may be more effective for stroke-affected patients. This could include reducing neuroinflammation through immune therapies, in combination with some pharmaceuticals specific to the patient's needs. Furthermore, sex differences are highly prevalent in ischemic stroke outcomes. These differences can inform us of the best sex-specific interventions, treatments, or techniques that should be used in healthcare to ensure lower mortality rates and higher quality of life for all. Therapeutic development for ischemic stroke is needed, and this review highlights that targeting the immune system could lead to better outcomes for patients.

Medical SciencesVol. 14(1)
Southern Illinois University Carbondale (US), Midwestern University (US), University of Arizona (US), Carleton University (CA)
Good health and well-being
Openalex Percentile: Top 54%
Neuroinflammation and Neurodegeneration Mechanisms
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