Ten-year medication-free remission of type 2 diabetes in a South Asian male using a culturally adapted low-carbohydrate diet: an N-of-1 longitudinal study

This report offers a detailed N-of-1 longitudinal characterization of decade-long, medication-free remission of T2D in a metabolically obese normal weight South Asian male. Observations at approximately 100 g per day carbohydrate intake suggest that moderate carbohydrate restriction may represent a physiologically plausible and culturally compatible approach for long-term metabolic management in similar phenotypes. While broader applicability requires validation in larger cohorts, these findings provide a rationale for further evaluation of moderate carbohydrate restriction as a feasible dietary strategy in South Asian and comparable settings.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-02-25
DOI
https://doi.org/10.3389/fnut.2026.1718156
Primary Topic
Diet and metabolism studies
Type
article
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article

Ten-year medication-free remission of type 2 diabetes in a South Asian male using a culturally adapted low-carbohydrate diet: an N-of-1 longitudinal study

Sharat Kolke, Jasmeet Kaur, Shashikant Iyengar, Anup Singh et al.
Frontiers in Nutrition
Diet and metabolism studies
article

Ten-year medication-free remission of type 2 diabetes in a South Asian male using a culturally adapted low-carbohydrate diet: an N-of-1 longitudinal study

Sharat Kolke, Jasmeet Kaur, Shashikant Iyengar, Anup Singh, R. K. Singh, I. Sahay, Mihir Raut, Arun Kumar
article en

Abstract

This report offers a detailed N-of-1 longitudinal characterization of decade-long, medication-free remission of T2D in a metabolically obese normal weight South Asian male. Observations at approximately 100 g per day carbohydrate intake suggest that moderate carbohydrate restriction may represent a physiologically plausible and culturally compatible approach for long-term metabolic management in similar phenotypes. While broader applicability requires validation in larger cohorts, these findings provide a rationale for further evaluation of moderate carbohydrate restriction as a feasible dietary strategy in South Asian and comparable settings.

Frontiers in NutritionVol. 13
MultiCare Health System (US), Max Super Speciality Hospital (IN), Gandhi Medical College (IN)
Zero hunger
Openalex Percentile: Top 42%
Diet and metabolism studies
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